7p34: Difference between revisions
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==SbmA-FabS11-1 in | ==Cryo-EM structure of the proton-dependent antibacterial peptide transporter SbmA-FabS11-1 in nanodiscs== | ||
<StructureSection load='7p34' size='340' side='right'caption='[[7p34]]' scene=''> | <StructureSection load='7p34' size='340' side='right'caption='[[7p34]], [[Resolution|resolution]] 3.59Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P34 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7p34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P34 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p34 OCA], [https://pdbe.org/7p34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p34 RCSB], [https://www.ebi.ac.uk/pdbsum/7p34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p34 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGW:(1R)-2-{[(S)-{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(HEXADECANOYLOXY)METHYL]ETHYL+(9Z)-OCTADEC-9-ENOATE'>PGW</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p34 OCA], [https://pdbe.org/7p34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p34 RCSB], [https://www.ebi.ac.uk/pdbsum/7p34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p34 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/SBMA_ECOLI SBMA_ECOLI]] Uptake of antimicrobial peptides. Required for the transport of microcin B17 (MccB17), microcin 25 (Mcc25) and proline-rich antimicrobial peptides (such as Cathelicidin-3 and Arasin 1) into the cell.<ref>PMID:17725560</ref> <ref>PMID:3543211</ref> <ref>PMID:7768835</ref> <ref>PMID:26860543</ref> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
[Figure: see text]. | |||
Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides.,Ghilarov D, Inaba-Inoue S, Stepien P, Qu F, Michalczyk E, Pakosz Z, Nomura N, Ogasawara S, Walker GC, Rebuffat S, Iwata S, Heddle JG, Beis K Sci Adv. 2021 Sep 10;7(37):eabj5363. doi: 10.1126/sciadv.abj5363. Epub 2021 Sep, 8. PMID:34516884<ref>PMID:34516884</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 7p34" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Beis K]] | [[Category: Beis, K]] | ||
[[Category: Ghilarov D]] | [[Category: Ghilarov, D]] | ||
[[Category: Antibiotic]] | |||
[[Category: Peptide transport]] | |||
[[Category: Proton transport]] | |||
[[Category: Slipt]] | |||
[[Category: Transport protein]] | |||
Revision as of 09:06, 29 September 2021
Cryo-EM structure of the proton-dependent antibacterial peptide transporter SbmA-FabS11-1 in nanodiscs
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