1uzu: Difference between revisions

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<StructureSection load='1uzu' size='340' side='right'caption='[[1uzu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1uzu' size='340' side='right'caption='[[1uzu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uzu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UZU FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uzu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UZU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=INR:2,3-DIOXO-1,1,2,3-TETRAHYDRO-2,3-BIINDOLE-5-SULFONIC+ACID'>INR</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=INR:2,3-DIOXO-1,1,2,3-TETRAHYDRO-2,3-BIINDOLE-5-SULFONIC+ACID'>INR</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a8i|1a8i]], [[1abb|1abb]], [[1axr|1axr]], [[1b4d|1b4d]], [[1bx3|1bx3]], [[1c50|1c50]], [[1c8k|1c8k]], [[1c8l|1c8l]], [[1e1y|1e1y]], [[1fs4|1fs4]], [[1ftq|1ftq]], [[1ftw|1ftw]], [[1fty|1fty]], [[1fu4|1fu4]], [[1fu7|1fu7]], [[1fu8|1fu8]], [[1gfz|1gfz]], [[1gg8|1gg8]], [[1ggn|1ggn]], [[1gpa|1gpa]], [[1gpb|1gpb]], [[1gpy|1gpy]], [[1h5u|1h5u]], [[1hlf|1hlf]], [[1k06|1k06]], [[1k08|1k08]], [[1kti|1kti]], [[1lwn|1lwn]], [[1lwo|1lwo]], [[1noi|1noi]], [[1noj|1noj]], [[1nok|1nok]], [[1p29|1p29]], [[1p2b|1p2b]], [[1p2d|1p2d]], [[1p2g|1p2g]], [[1pyg|1pyg]], [[2amv|2amv]], [[2gpa|2gpa]], [[2gpb|2gpb]], [[2gpn|2gpn]], [[2pri|2pri]], [[2prj|2prj]], [[2skc|2skc]], [[2skd|2skd]], [[2ske|2ske]], [[3amv|3amv]], [[3gpb|3gpb]], [[4gpb|4gpb]], [[5gpb|5gpb]], [[6gpb|6gpb]], [[7gpb|7gpb]], [[8gpb|8gpb]], [[9gpb|9gpb]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1a8i|1a8i]], [[1abb|1abb]], [[1axr|1axr]], [[1b4d|1b4d]], [[1bx3|1bx3]], [[1c50|1c50]], [[1c8k|1c8k]], [[1c8l|1c8l]], [[1e1y|1e1y]], [[1fs4|1fs4]], [[1ftq|1ftq]], [[1ftw|1ftw]], [[1fty|1fty]], [[1fu4|1fu4]], [[1fu7|1fu7]], [[1fu8|1fu8]], [[1gfz|1gfz]], [[1gg8|1gg8]], [[1ggn|1ggn]], [[1gpa|1gpa]], [[1gpb|1gpb]], [[1gpy|1gpy]], [[1h5u|1h5u]], [[1hlf|1hlf]], [[1k06|1k06]], [[1k08|1k08]], [[1kti|1kti]], [[1lwn|1lwn]], [[1lwo|1lwo]], [[1noi|1noi]], [[1noj|1noj]], [[1nok|1nok]], [[1p29|1p29]], [[1p2b|1p2b]], [[1p2d|1p2d]], [[1p2g|1p2g]], [[1pyg|1pyg]], [[2amv|2amv]], [[2gpa|2gpa]], [[2gpb|2gpb]], [[2gpn|2gpn]], [[2pri|2pri]], [[2prj|2prj]], [[2skc|2skc]], [[2skd|2skd]], [[2ske|2ske]], [[3amv|3amv]], [[3gpb|3gpb]], [[4gpb|4gpb]], [[5gpb|5gpb]], [[6gpb|6gpb]], [[7gpb|7gpb]], [[8gpb|8gpb]], [[9gpb|9gpb]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphorylase Phosphorylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.1 2.4.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uzu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uzu OCA], [http://pdbe.org/1uzu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uzu RCSB], [http://www.ebi.ac.uk/pdbsum/1uzu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uzu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uzu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uzu OCA], [https://pdbe.org/1uzu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uzu RCSB], [https://www.ebi.ac.uk/pdbsum/1uzu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uzu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.  
[[https://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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