3k79: Difference between revisions
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==C38A, C52V Cysteine-Free Variant of Rop (Rom)== | ==C38A, C52V Cysteine-Free Variant of Rop (Rom)== | ||
<StructureSection load='3k79' size='340' side='right' caption='[[3k79]], [[Resolution|resolution]] 1.96Å' scene=''> | <StructureSection load='3k79' size='340' side='right'caption='[[3k79]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3k79]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3k79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K79 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rop ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rop ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k79 OCA], [https://pdbe.org/3k79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k79 RCSB], [https://www.ebi.ac.uk/pdbsum/3k79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k79 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX]] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacillus coli migula 1895]] | [[Category: Bacillus coli migula 1895]] | ||
[[Category: Large Structures]] | |||
[[Category: Hari, S B]] | [[Category: Hari, S B]] | ||
[[Category: Magliery, T J]] | [[Category: Magliery, T J]] | ||