1vbx: Difference between revisions

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<StructureSection load='1vbx' size='340' side='right'caption='[[1vbx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='1vbx' size='340' side='right'caption='[[1vbx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vbx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VBX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vbx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VBX FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1drz|1drz]], [[1cx0|1cx0]], [[1vby|1vby]], [[1vbz|1vbz]], [[1vc0|1vc0]], [[1sjf|1sjf]], [[1vc5|1vc5]], [[1vc6|1vc6]], [[1vc7|1vc7]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1drz|1drz]], [[1cx0|1cx0]], [[1vby|1vby]], [[1vbz|1vbz]], [[1vc0|1vc0]], [[1sjf|1sjf]], [[1vc5|1vc5]], [[1vc6|1vc6]], [[1vc7|1vc7]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbx OCA], [http://pdbe.org/1vbx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vbx RCSB], [http://www.ebi.ac.uk/pdbsum/1vbx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbx OCA], [https://pdbe.org/1vbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vbx RCSB], [https://www.ebi.ac.uk/pdbsum/1vbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN]] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>   
[[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN]] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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