2pf2: Difference between revisions

<table><tr><td colspan='2'>[[2pf2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. The January 2002 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Thrombin''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2002_1 10.2210/rcsb_pdb/mom_2002_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PF2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PF2 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pf2 OCA], [http://pdbe.org/2pf2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pf2 RCSB], [http://www.ebi.ac.uk/pdbsum/2pf2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pf2 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN]] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).  

*[[Thrombin|Thrombin]]