Sandbox Reserved 1688: Difference between revisions

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Catalytic Site –  
Catalytic Site –  


While the fingers domain of the NS5B protein is structurally different than other RdRps, the catalytic site (largely housed in the palm region) remain structural conserved.
The fingers domain help with guiding the RNA into the <scene name='NS5B/Native_ns5b/7'>active site aspartates (220, 318 and 319)</scene>.
 




<scene name='NS5B/Native_ns5b/7'>active site aspartates (220, 318 and 319)</scene>


<scene name='89/891378/Palmcordmagnesium/3'>residues that coordinate divalent cations </scene>
<scene name='89/891378/Palmcordmagnesium/3'>residues that coordinate divalent cations </scene>


<scene name='89/891378/Thumbregion/1'>Thumb Region</scene>.
<scene name='89/891378/Thumbregion/1'>Thumb Region</scene>.