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==Crystal structure of the R43L mutant of LolA in the closed form==
==Crystal structure of the R43L mutant of LolA in the closed form==
<StructureSection load='2zpc' size='340' side='right' caption='[[2zpc]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='2zpc' size='340' side='right'caption='[[2zpc]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zpc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZPC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zpc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZPC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1iwl|1iwl]], [[1ua8|1ua8]], [[2zpd|2zpd]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1iwl|1iwl]], [[1ua8|1ua8]], [[2zpd|2zpd]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lolA, lplA, yzzV, b0891, JW0874 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lolA, lplA, yzzV, b0891, JW0874 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpc OCA], [http://pdbe.org/2zpc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zpc RCSB], [http://www.ebi.ac.uk/pdbsum/2zpc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpc OCA], [https://pdbe.org/2zpc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zpc RCSB], [https://www.ebi.ac.uk/pdbsum/2zpc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI]] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref>  May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>   
[[https://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI]] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref>  May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Miki, K]]
[[Category: Miki, K]]
[[Category: Oguchi, Y]]
[[Category: Oguchi, Y]]
Retrieved from "https://proteopedia.org/2zpc"