2x4f: Difference between revisions
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<StructureSection load='2x4f' size='340' side='right'caption='[[2x4f]], [[Resolution|resolution]] 2.67Å' scene=''> | <StructureSection load='2x4f' size='340' side='right'caption='[[2x4f]], [[Resolution|resolution]] 2.67Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2x4f]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2x4f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X4F FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16X:4-(2-AMINO-4-METHYL-1,3-THIAZOL-5-YL)-N-(3-DIOXAZIRIDIN-3-YLPHENYL)PYRIMIDIN-2-AMINE'>16X</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=16X:4-(2-AMINO-4-METHYL-1,3-THIAZOL-5-YL)-N-(3-DIOXAZIRIDIN-3-YLPHENYL)PYRIMIDIN-2-AMINE'>16X</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x4f OCA], [https://pdbe.org/2x4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x4f RCSB], [https://www.ebi.ac.uk/pdbsum/2x4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x4f ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
Revision as of 08:35, 10 November 2021
The Crystal Structure of the human myosin light chain kinase LOC340156.
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human
- Large Structures
- Non-specific serine/threonine protein kinase
- Arrowsmith, C H
- Bountra, C
- Chaikuad, A
- Cocking, R
- Daga, N
- Delft, F von
- Edwards, A M
- Elkins, J M
- Fedorov, O
- Gileadi, O
- Knapp, S
- Krojer, T
- Mahajan, P
- Muniz, J R.C
- Rellos, P
- Shrestha, B
- Ugochukwu, E
- Wang, J
- Weigelt, J
- Yue, W
- Breast cancer
- Kinase
- Lung
- Myosin
- Transferase
