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==Structural and Mechanistic Analysis of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway==
==Structural and Mechanistic Analysis of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway==
<StructureSection load='2xm7' size='340' side='right' caption='[[2xm7]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
<StructureSection load='2xm7' size='340' side='right'caption='[[2xm7]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xm7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strrc Strrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XM7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XM7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xm7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strrc Strrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XM7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=34H:(2R)-2-HYDROXY-3-(4-HYDROXYPHENYL)PROPANOIC+ACID'>34H</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=34H:(2R)-2-HYDROXY-3-(4-HYDROXYPHENYL)PROPANOIC+ACID'>34H</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xm5|2xm5]], [[2xlq|2xlq]], [[2xly|2xly]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xm5|2xm5]], [[2xlq|2xlq]], [[2xly|2xly]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xm7 OCA], [http://pdbe.org/2xm7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xm7 RCSB], [http://www.ebi.ac.uk/pdbsum/2xm7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xm7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xm7 OCA], [https://pdbe.org/2xm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xm7 RCSB], [https://www.ebi.ac.uk/pdbsum/2xm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xm7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CLOQ_STRRC CLOQ_STRRC]] Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the clorobiocin biosynthesis pathway. Clorobiocin is an aminocoumarin family antibiotic.<ref>PMID:12618544</ref>   
[[https://www.uniprot.org/uniprot/CLOQ_STRRC CLOQ_STRRC]] Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the clorobiocin biosynthesis pathway. Clorobiocin is an aminocoumarin family antibiotic.<ref>PMID:12618544</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Strrc]]
[[Category: Strrc]]
[[Category: Heide, L]]
[[Category: Heide, L]]
Retrieved from "https://proteopedia.org/2xm7"