2y1r: Difference between revisions

<table><tr><td colspan='2'>[[2y1r]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y1R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y1R FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SRT:S,R+MESO-TARTARIC+ACID'>SRT</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y1q|2y1q]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y1r OCA], [http://pdbe.org/2y1r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y1r RCSB], [http://www.ebi.ac.uk/pdbsum/2y1r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y1r ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/CLPC_BACSU CLPC_BACSU]] Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK. [[http://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU]] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref>