2bbm: Difference between revisions

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<StructureSection load='2bbm' size='340' side='right'caption='[[2bbm]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='2bbm' size='340' side='right'caption='[[2bbm]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2bbm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. The August 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Calmodulin''  by Shuchismita Dutta and David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_8 10.2210/rcsb_pdb/mom_2003_8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBM FirstGlance]. <br>
<table><tr><td colspan='2'>[[2bbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. The August 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Calmodulin''  by Shuchismita Dutta and David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_8 10.2210/rcsb_pdb/mom_2003_8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bbn|2bbn]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bbn|2bbn]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbm OCA], [http://pdbe.org/2bbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bbm RCSB], [http://www.ebi.ac.uk/pdbsum/2bbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbm OCA], [https://pdbe.org/2bbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbm RCSB], [https://www.ebi.ac.uk/pdbsum/2bbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CALM_DROME CALM_DROME]] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. [[http://www.uniprot.org/uniprot/MYLK2_RABIT MYLK2_RABIT]] Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain.  
[[https://www.uniprot.org/uniprot/CALM_DROME CALM_DROME]] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. [[https://www.uniprot.org/uniprot/MYLK2_RABIT MYLK2_RABIT]] Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
*[[NMR Ensembles of Models|NMR Ensembles of Models]]
*[[Structural alignment tools|Structural alignment tools]]
== References ==
== References ==
<references/>
<references/>