Transmembrane protease serine 2: Difference between revisions
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=== Viral entry === | === Viral entry === | ||
TMPRSS2 facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. As human TMPRSS2 is expressed in cells of the respiratory tracts, in addition to the epithelia of the gastrointestinal and urogenital systems, it mediates the entry of several viruses related to respiratory diseases into the host cells, including Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus). | |||
====SARS-CoV-2==== | |||
== Structure == | == Structure == | ||
