2an7: Difference between revisions

<table><tr><td colspan='2'>[[2an7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AN7 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2an7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2an7 OCA], [http://pdbe.org/2an7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2an7 RCSB], [http://www.ebi.ac.uk/pdbsum/2an7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2an7 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PARD_ECOLX PARD_ECOLX]] Antitoxin component of a toxin-antitoxin (TA) module involved in plasmid partition. Inhibits the anti-DNA gyrase activity of toxin ParE; reverses and restores gyrase catalytic activity in vitro. The parDE operon alone is capable of stabilizing an RK2-derived minireplicon under defined growth conditions in several different Gram-negative bacteria. It does so by the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system. Binds its own promoter, autorepressing it; gentically only ParD is required for full autorepression.<ref>PMID:12010492</ref> <ref>PMID:1459960</ref> <ref>PMID:8133518</ref> <ref>PMID:8631720</ref>