2klc: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA]. For a guided tour on the structure components use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2KLC FirstGlance].

<table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=2KLC FirstGlance].

</td></tr><tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">DA41, PLIC1, UBQLN1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

</td></tr><tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">DA41, PLIC1, UBQLN1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2klc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klc OCA], [~~http~~://pdbe.org/2klc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2klc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2klc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2klc ProSAT]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=2klc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klc OCA], [https://pdbe.org/2klc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2klc RCSB], [https://www.ebi.ac.uk/pdbsum/2klc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2klc ProSAT]</td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN]] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.

[[https://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN]] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

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 <StructureSection load='2klc' size='340' side='right'caption='[[2klc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KLC FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2klc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLC FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DA41, PLIC1, UBQLN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DA41, PLIC1, UBQLN1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2klc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klc OCA], [http://pdbe.org/2klc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2klc RCSB], [http://www.ebi.ac.uk/pdbsum/2klc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2klc ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2klc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2klc OCA], [https://pdbe.org/2klc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2klc RCSB], [https://www.ebi.ac.uk/pdbsum/2klc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2klc ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN]] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
+[[https://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN]] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]