Ceramide: Difference between revisions

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<StructureSection load='' scene='Acid-beta-glucosidase/Overview2/2' size='350' caption='Human acid-β-glucosidase (PDB code [[1ogs]])'

>

~~This~~ is a ~~default text for your page '''Ceramide'''. Click above on '''edit this page''' to modify~~. ~~Be careful with~~ the ~~< and > signs.~~

*[[Sphingomyelinase]] (SMase) or sphingomyelin phosphodiesterase is a hydrolase involved in sphingolipid metabolism. It catalyzes the breakdown of sphingomyelin (SM) to phosphocholine and ceramide<ref>PMID:11001563</ref>.

~~You may include any references to papers as in: the use~~ of ~~JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or~~ to ~~the article describing Jmol~~ <ref>PMID:~~21638687~~</ref> ~~to the rescue~~.

~~== Function ==~~

*[[Acid-beta-glucosidase]] or '''glucosylceramidase''' is a lysozomal enzyme (EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45]), which cleaves glucosylceramide to glucose and ceramide. It catalyzes hydrolysis of the sphingolipid, <scene name='Acid-beta-glucosidase/Cv/3'>glucosylceramide (GlcCer)</scene>, to <scene name='Acid-beta-glucosidase/Cv/2'>glucose and ceramide</scene> at the acidic pH prevailing within the lysosome. <scene name='Acid-beta-glucosidase/Cv/4'>Click here to see animation of this reaction</scene>.

*The molecular function of [[galactosylceramidase]] is hydrolysis of a O-glycosyl bond to remove galactose from ceramide and other sphingolipids.

~~== Disease ==~~

~~== Relevance ==~~

~~== Structural highlights ==~~

~~This~~ is a ~~sample scene created with SAT~~ to <scene name="/12/~~3456/Sample/1"~~>~~color~~</scene> ~~by Group~~, ~~and another~~ to ~~make~~ <scene name="/12/~~3456~~/~~Sample~~/2">~~a transparent representation~~</scene> of ~~the protein. You can make your own scenes on SAT starting~~ from ~~scratch or loading~~ and ~~editing one of these sample scenes~~.

</StructureSection>

== References ==

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@@ Line 1: / Line 1: @@
 <StructureSection load='' scene='Acid-beta-glucosidase/Overview2/2' size='350'  caption='Human acid-β-glucosidase (PDB code [[1ogs]])'
 >
-This is a default text for your page '''Ceramide'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
+*[[Sphingomyelinase]] (SMase) or sphingomyelin phosphodiesterase is a hydrolase involved in sphingolipid metabolism. It catalyzes the breakdown of sphingomyelin (SM) to phosphocholine and ceramide<ref>PMID:11001563</ref>.
-You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
-== Function ==
+*[[Acid-beta-glucosidase]] or '''glucosylceramidase''' is a lysozomal enzyme (EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.45 3.2.1.45]), which cleaves glucosylceramide to glucose and ceramide. It catalyzes hydrolysis of the sphingolipid, <scene name='Acid-beta-glucosidase/Cv/3'>glucosylceramide (GlcCer)</scene>, to <scene name='Acid-beta-glucosidase/Cv/2'>glucose and ceramide</scene> at the acidic pH prevailing within the lysosome. <scene name='Acid-beta-glucosidase/Cv/4'>Click here to see animation of this reaction</scene>.
+*The molecular function of [[galactosylceramidase]] is hydrolysis of a O-glycosyl bond to remove galactose from ceramide and other sphingolipids.
-== Disease ==
-== Relevance ==
-== Structural highlights ==
-This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
 </StructureSection>
 == References ==
 <references/>