Fel d 1: Difference between revisions

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In the 3D scene of the asymmetric unit of Fel d 1 it is possible to <scene name="/12/3456/Sample/1">color</scene> by group, make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein Fel d 1 and visualize four [http://www.chemspider.com/Chemical-Structure.13884973.html MPD] molecules (used in the crystallization of Fel d 1) <ref name="[1]"/> <ref>DOI 10.1002/ijch.201300024</ref> <ref>PMID:21638687</ref>.
In the 3D scene of the asymmetric unit of Fel d 1 it is possible to <scene name="/12/3456/Sample/1">color</scene> by group, make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein Fel d 1 and visualize four [http://www.chemspider.com/Chemical-Structure.13884973.html MPD] molecules (used in the crystallization of Fel d 1) <ref name="[1]"/> <ref>DOI 10.1002/ijch.201300024</ref> <ref>PMID:21638687</ref>.
Figure 5 shows the three-dimensional configuration of Fel d 1.
[[Image:Fel d 1 3D.png | thumb | center | 500px | '''Figure 5.''' Three-dimensional configuration of Fel d 1. (Source: PyMOL 2.5.2)]]


=='''Treatment'''==
=='''Treatment'''==


[https://acaai.org/allergies/management-treatment/allergy-immunotherapy/ Immunotherapy], or allergy vaccination, which is based on repeated subcutaneous injections of cat hair extracts has been shown to be effective in the curative treatment of allergy. However, in addition to being a time-consuming treatment, it can cause serious side effects such as asthma attacks and anaphylactic shock <ref name="[1]"/><ref name="[4]"/>.
[https://acaai.org/allergies/management-treatment/allergy-immunotherapy/ Immunotherapy], or allergy vaccination, which is based on repeated subcutaneous injections of cat hair extracts has been shown to be effective in the curative treatment of allergy. However, in addition to being a time-consuming treatment, it can cause serious side effects such as asthma attacks and anaphylactic shock <ref name="[1]"/><ref name="[4]"/>.
Additionally, to add to the immunotherapy treatment, there is a cat food supplemented with anti-Fel d 1 IgY, which significantly reduces active Fel d 1 levels. Figure 5 shows the three-dimensional configuration of Fel d 1 (a) and the structure of Fel d 1 linked to two anti-Fel d 1 IgY antibodies (b) <ref name="[3]"/>.
Additionally, to add to the immunotherapy treatment, there is a cat food supplemented with anti-Fel d 1 IgY, which significantly reduces active Fel d 1 levels.
 
[[Image:Anticorpos.jpg | thumb | center | 500px | '''Figure 5.''' (a) Three-dimensional configuration of Fel d 1 (b) Fel d 1 linked to two anti-Fel d 1 IgY antibodies <ref name="[3]"/>.]]




== '''References''' ==
== '''References''' ==
<references/>
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