Sandbox Reserved 1697: Difference between revisions
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== Other important features == | == Other important features == | ||
The protein 7KIR is a protype member of proteins that work in inositol signaling, specifically dephosphorylating inositol to stop inositol signaling. The protein that the paper primarily mentions is <scene name='89/892740/1inp/1'>1INP</scene>, all of the proteins in this family share a motif, DPID X T. The X in the motif means that there can be any amino acid in there, in 1INP it is alanine while in <scene name='89/892740/7kir_catalytic_amino_acids/1'>7KIR</scene> is aspartic acid. The mutation in these proteins have no functional impact on the protein's ability to dephosphorylate inositol. | The protein 7KIR is a protype member of proteins that work in inositol signaling, specifically dephosphorylating inositol to stop inositol signaling. The protein that the paper primarily mentions is <scene name='89/892740/1inp/1'>1INP</scene>, all of the proteins in this family share a motif, DPID X T. The X in the motif means that there can be any amino acid in there, in 1INP it is alanine while in <scene name='89/892740/7kir_catalytic_amino_acids/1'>7KIR</scene> is aspartic acid. The mutation in these proteins have no functional impact on the protein's ability to dephosphorylate inositol. | ||
One of the unique things of this enzyme is its use of metal ions, the <scene name='89/892740/Interact_with_metal_ions/1'>amino acids bond with the metal ions</scene> that then bind with the water. The water attacks the phosphate which causes the inositol to dephosphorylate the substrate. The catalytic amino acids in enzyme are mainly polar which causes the magnesium ions to better bond with them. | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
