Sandbox Reserved 1091: Difference between revisions

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In the '''kallikrein/kinin system''', the ASP induce the production of kinin from kininogen (low MW or high MW). The kinin also release caused edema at the infection site and shock in the circulation. The schematic representation of this action is represented : [http://www.degruyter.com/viewimg/j/bchm.2017.398.issue-10/hsz-2016-0344/hsz-2016-0344.xml?img=graphic/j_hsz-2016-0344_fig_002.jpg '''acting points of ASP in the kinin system''' ]

Experiments have been done in order to try to reduce the virulence activity of ASP. It has been demonstrated that the [http://fr.wikipedia.org/wiki/Alpha-2_macroglobuline α2-macroglobulin], a plasma protein, can limit ASP activity. This protein can bind to ASP which is ~~also~~ inactivated. <ref>Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin. Murakami Y et al. Biol Chem. 393(10):1193-200 (2012)</ref>

Experiments have been done in order to try to reduce the virulence activity of ASP. It has been demonstrated that the [http://fr.wikipedia.org/wiki/Alpha-2_macroglobuline α2-macroglobulin], a plasma protein, can limit ASP activity. This protein can bind to ASP which is thus inactivated. <ref>Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin. Murakami Y et al. Biol Chem. 393(10):1193-200 (2012)</ref>

Sandbox Reserved 1091: Difference between revisions

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Revision as of 09:00, 28 December 2021 view source Tavernier Eliette (talk \| contribs) 23 edits No edit summary ← Older edit		Revision as of 09:25, 28 December 2021 view source Tavernier Eliette (talk \| contribs) 23 edits No edit summary Newer edit →
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	In the '''kallikrein/kinin system''', the ASP induce the production of kinin from kininogen (low MW or high MW). The kinin also release caused edema at the infection site and shock in the circulation. The schematic representation of this action is represented : [http://www.degruyter.com/viewimg/j/bchm.2017.398.issue-10/hsz-2016-0344/hsz-2016-0344.xml?img=graphic/j_hsz-2016-0344_fig_002.jpg '''acting points of ASP in the kinin system''' ]		In the '''kallikrein/kinin system''', the ASP induce the production of kinin from kininogen (low MW or high MW). The kinin also release caused edema at the infection site and shock in the circulation. The schematic representation of this action is represented : [http://www.degruyter.com/viewimg/j/bchm.2017.398.issue-10/hsz-2016-0344/hsz-2016-0344.xml?img=graphic/j_hsz-2016-0344_fig_002.jpg '''acting points of ASP in the kinin system''' ]

	Experiments have been done in order to try to reduce the virulence activity of ASP. It has been demonstrated that the [http://fr.wikipedia.org/wiki/Alpha-2_macroglobuline α2-macroglobulin], a plasma protein, can limit ASP activity. This protein can bind to ASP which is ~~also~~ inactivated. <ref>Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin. Murakami Y et al. Biol Chem. 393(10):1193-200 (2012)</ref>		Experiments have been done in order to try to reduce the virulence activity of ASP. It has been demonstrated that the [http://fr.wikipedia.org/wiki/Alpha-2_macroglobuline α2-macroglobulin], a plasma protein, can limit ASP activity. This protein can bind to ASP which is thus inactivated. <ref>Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin. Murakami Y et al. Biol Chem. 393(10):1193-200 (2012)</ref>