FirstGlance/Visualizing Conservation: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) |
||
| Line 82: | Line 82: | ||
==Conservation of Residues Binding Ligand/Substrate== | ==Conservation of Residues Binding Ligand/Substrate== | ||
For this example, we'll use [[acetylcholinesterase]] complexed to the [https://en.wikipedia.org/wiki/VX_(nerve_agent) inhibitor VX], crystal structure [[6cqz]]. | FirstGlance provides an easy and powerful tool to explore residues contacting any specified portion of the model. For this example, we'll use [[acetylcholinesterase]] complexed to the [https://en.wikipedia.org/wiki/VX_(nerve_agent) inhibitor VX], crystal structure [[6cqz]]. | ||
:[https://www.bioinformatics.org/firstglance/fgij3.8beta2/fg.htm?mol=6cqz_consurf1641072297_pipe.pdb Display 6CQZ ConSurf Result in FirstGlance 3.8Beta2] | :[https://www.bioinformatics.org/firstglance/fgij3.8beta2/fg.htm?mol=6cqz_consurf1641072297_pipe.pdb Display 6CQZ ConSurf Result in FirstGlance 3.8Beta2] | ||
From the ''ConSurf View'', go to the FirstGlance Control Panel | We'll look at the conservation of the residues that contact the ligand/inhibitor VX. From the ''ConSurf View'', go to the FirstGlance Control Panel. | ||
<table class="wikitable" align="right"><tr><td> | <table class="wikitable" align="right"><tr><td> | ||
