2bg9: Difference between revisions
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<SX load='2bg9' size='340' side='right' viewer='molstar' caption='[[2bg9]], [[Resolution|resolution]] 4.00Å' scene=''> | <SX load='2bg9' size='340' side='right' viewer='molstar' caption='[[2bg9]], [[Resolution|resolution]] 4.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bg9]] is a 5 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2bg9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Torpedo_marmorata Torpedo marmorata]. The November 2005 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Acetylcholine Receptor'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2005_11 10.2210/rcsb_pdb/mom_2005_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BG9 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1l4w|1l4w]], [[1ljz|1ljz]], [[1oed|1oed]], [[1i9b|1i9b]], [[1uv6|1uv6]], [[1f3r|1f3r]], [[1tor|1tor]], [[1tos|1tos]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1l4w|1l4w]], [[1ljz|1ljz]], [[1oed|1oed]], [[1i9b|1i9b]], [[1uv6|1uv6]], [[1f3r|1f3r]], [[1tor|1tor]], [[1tos|1tos]]</div></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bg9 OCA], [https://pdbe.org/2bg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bg9 RCSB], [https://www.ebi.ac.uk/pdbsum/2bg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bg9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ACHA_TORMA ACHA_TORMA]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptor]] | *[[Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptor]] | ||
*[[5-hydroxytryptamine receptor|5-hydroxytryptamine receptor]] | *[[5-hydroxytryptamine receptor|5-hydroxytryptamine receptor]] | ||