Sandbox Reserved 1650: Difference between revisions
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=== Expression of the TG gene=== | === Expression of the TG gene=== | ||
In humans, TG is coded by a large gene roughly '''300 kb long''', located on chromosome 8. The number of exons has been estimated to be around 48, each of which is separated by introns varying in size up to 64 kb. TG gene | In humans, TG is coded by a large gene roughly '''300 kb long''', located on chromosome 8. The number of exons has been estimated to be around 48, each of which is separated by introns varying in size up to 64 kb. TG gene expression is controlled positively by '''thyro-tropin (TSH)''' through the modulation of the intra-cellular levels of '''cyclic adenosine monophosphate (cAMP)''' via its receptor (TSHr) located at the basal membrane of the cell.<ref>PMID: 11581009</ref> | ||
=== Post-translational modifications === | === Post-translational modifications === | ||
