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==Crystal structure of the Escherichia coli transcriptional repressor ascG==
==Crystal structure of the Escherichia coli transcriptional repressor ascG==
<StructureSection load='3brq' size='340' side='right' caption='[[3brq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3brq' size='340' side='right'caption='[[3brq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3brq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BRQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3brq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ascG, b2714, JW5434 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ascG, b2714, JW5434 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3brq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brq OCA], [http://pdbe.org/3brq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3brq RCSB], [http://www.ebi.ac.uk/pdbsum/3brq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3brq ProSAT], [http://www.topsan.org/Proteins/MCSG/3brq TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3brq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brq OCA], [https://pdbe.org/3brq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3brq RCSB], [https://www.ebi.ac.uk/pdbsum/3brq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3brq ProSAT], [https://www.topsan.org/Proteins/MCSG/3brq TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ASCG_ECOLI ASCG_ECOLI]] Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene.  
[[https://www.uniprot.org/uniprot/ASCG_ECOLI ASCG_ECOLI]] Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Edwards, A M]]
[[Category: Edwards, A M]]
[[Category: Evdokimova, E]]
[[Category: Evdokimova, E]]

Latest revision as of 08:23, 19 January 2022

Crystal structure of the Escherichia coli transcriptional repressor ascG

3brq, resolution 2.00Å

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