Sandbox Reserved 1649: Difference between revisions
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NMDA receptors are inhibited by ethanol. Mutagenesis of an F residue in the transmembrane domain has made it possible to characterize the role of the latter in this inhibition. On the other hand, the phenylalanine residue at position 639 is replaced by an alanine in the transmembrane domain (in part M3) and the results show significantly less inhibition by ethanol of NMDA compared to wild type receptors.<ref name="ethanol inhibition">DOI 10.1074 / jbc.M102800200</ref> | NMDA receptors are inhibited by ethanol. [https://en.wikipedia.org/wiki/Mutagenesis Mutagenesis] of an F residue in the transmembrane domain has made it possible to characterize the role of the latter in this inhibition. On the other hand, the phenylalanine residue at position 639 is replaced by an alanine in the transmembrane domain (in part M3) and the results show significantly less inhibition by ethanol of NMDA compared to wild type receptors.<ref name="ethanol inhibition">DOI 10.1074 / jbc.M102800200</ref> | ||
== Disease == | == Disease == | ||
