Sandbox Reserved 1644: Difference between revisions

[https://en.wikipedia.org/wiki/Mitochondrion Mitochondrial] Lon [https://en.wikipedia.org/wiki/Protease protease] is an '''ATP-dependent serine protease''' (an enzyme that hydrolyses proteins and polypeptides) involved '''in the selective degradation of misfolded proteins'''. [https://en.wikipedia.org/wiki/LONP1 LONP1] situated on chromosome 19 is the nuclear gene encoding mitochondrial Lon protein. The single species of [https://en.wikipedia.org/wiki/Messenger_RNA mRNA] of this protein is found in the mitochondrial matrix. This protein from human tissues has a molecular mass of 100 [https://en.wikipedia.org/wiki/Dalton_(unit) kDA].</p> It is involved in the selective degradation of misfolded proteins and also coordinates key processes through targeted proteolysis of folded proteins .Their only species of mRNA is found in the mitochondrial matrix and their proteolytic domain is the center of the Lon protease activity.