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==CRYSTAL STRUCTURE OF SUGAR-BINDING TRANSCRIPTIONAL REGULATOR (LACI FAMILY) FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE==
==CRYSTAL STRUCTURE OF SUGAR-BINDING TRANSCRIPTIONAL REGULATOR (LACI FAMILY) FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE==
<StructureSection load='3dbi' size='340' side='right' caption='[[3dbi]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='3dbi' size='340' side='right'caption='[[3dbi]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3dbi]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DBI FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DBI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbi OCA], [https://pdbe.org/3dbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dbi RCSB], [https://www.ebi.ac.uk/pdbsum/3dbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dbi ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3dbi TOPSAN]</span></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LACI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dbi OCA], [http://pdbe.org/3dbi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dbi RCSB], [http://www.ebi.ac.uk/pdbsum/3dbi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dbi ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3dbi TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ASCG_ECOLI ASCG_ECOLI]] Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Freeman, J]]
[[Category: Freeman J]]
[[Category: Koss, J]]
[[Category: Koss J]]
[[Category: Maletic, M]]
[[Category: Maletic M]]
[[Category: Structural genomic]]
[[Category: Ozyurt S]]
[[Category: Ozyurt, S]]
[[Category: Patskovsky Y]]
[[Category: Patskovsky, Y]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Wasserman SR]]
[[Category: Wasserman, S R]]
[[Category: Wu B]]
[[Category: Wu, B]]
[[Category: Dna-binding]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Repressor]]
[[Category: Sugar-binding transcriptional regulator]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]

Revision as of 07:59, 2 February 2022

CRYSTAL STRUCTURE OF SUGAR-BINDING TRANSCRIPTIONAL REGULATOR (LACI FAMILY) FROM ESCHERICHIA COLI COMPLEXED WITH PHOSPHATE

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