7c4i: Difference between revisions

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==High resolution structure of BRPF1 ~~bromodomain~~==

==High resolution structure of BRPF1 Bromo Domain from Biortus==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance].

<table><tr><td colspan='2'>[[7c4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [~~http~~://pdbe.org/7c4i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</td></tr>

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">BRPF1, BR140 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [https://pdbe.org/7c4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [https://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</td></tr>

</table>

== Function ==

[[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>

==See Also==

*[[Peregrin|Peregrin]]

== References ==

__TOC__

</StructureSection>

[[Category: Human]]

[[Category: Large Structures]]

[[Category: Lin D]]

[[Category: Lin, D]]

[[Category: Lv Z]]

[[Category: Lv, Z]]

[[Category: Wang F]]

[[Category: Wang, F]]

[[Category: Zhu B]]

[[Category: Zhu, B]]

[[Category: Dna binding protein]]

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-==High resolution structure of BRPF1 bromodomain==
+==High resolution structure of BRPF1 Bromo Domain from Biortus==
-<StructureSection load='7c4i' size='340' side='right'caption='[[7c4i]]' scene=''>
+<StructureSection load='7c4i' size='340' side='right'caption='[[7c4i]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7c4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [http://pdbe.org/7c4i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [http://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</span></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRPF1, BR140 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [https://pdbe.org/7c4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [https://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</span></td></tr>
 </table>
+== Function ==
+[[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
+==See Also==
+*[[Peregrin|Peregrin]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Human]]
 [[Category: Large Structures]]
-[[Category: Lin D]]
+[[Category: Lin, D]]
-[[Category: Lv Z]]
+[[Category: Lv, Z]]
-[[Category: Wang F]]
+[[Category: Wang, F]]
-[[Category: Zhu B]]
+[[Category: Zhu, B]]
+[[Category: Dna binding protein]]