2lbv: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[2lbv]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cotja Cotja]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LBV FirstGlance]. <br>

<table><tr><td colspan='2'>[[2lbv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cotja Cotja]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LBV FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACD:ARACHIDONIC+ACID'>ACD</scene>, <scene name='pdbligand=EB4:N,N,N-[(3S,7S,11S)-2,6,10-TRIOXO-1,5,9-TRIOXACYCLODODECANE-3,7,11-TRIYL]TRIS(2,3-DIHYDROXYBENZAMIDE)'>EB4</scene>, <scene name='pdbligand=GA:GALLIUM+(III)+ION'>GA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2lbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbv OCA], [~~http~~://pdbe.org/2lbv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lbv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lbv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbv ProSAT]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbv OCA], [https://pdbe.org/2lbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lbv RCSB], [https://www.ebi.ac.uk/pdbsum/2lbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbv ProSAT]</span></td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/EXFAB_COTJA EXFAB_COTJA]] Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor.<ref>PMID:20826777</ref> <ref>PMID:21951132</ref>

[[https://www.uniprot.org/uniprot/EXFAB_COTJA EXFAB_COTJA]] Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor.<ref>PMID:20826777</ref> <ref>PMID:21951132</ref>

== Publication Abstract from PubMed ==

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 <StructureSection load='2lbv' size='340' side='right'caption='[[2lbv]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2lbv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cotja Cotja]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LBV FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2lbv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cotja Cotja]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LBV FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACD:ARACHIDONIC+ACID'>ACD</scene>, <scene name='pdbligand=EB4:N,N,N-[(3S,7S,11S)-2,6,10-TRIOXO-1,5,9-TRIOXACYCLODODECANE-3,7,11-TRIYL]TRIS(2,3-DIHYDROXYBENZAMIDE)'>EB4</scene>, <scene name='pdbligand=GA:GALLIUM+(III)+ION'>GA</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2lbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbv OCA], [http://pdbe.org/2lbv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lbv RCSB], [http://www.ebi.ac.uk/pdbsum/2lbv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbv ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbv OCA], [https://pdbe.org/2lbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lbv RCSB], [https://www.ebi.ac.uk/pdbsum/2lbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbv ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/EXFAB_COTJA EXFAB_COTJA]] Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor.<ref>PMID:20826777</ref> <ref>PMID:21951132</ref>
+[[https://www.uniprot.org/uniprot/EXFAB_COTJA EXFAB_COTJA]] Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor.<ref>PMID:20826777</ref> <ref>PMID:21951132</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==