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==Crystal structure of Probable 2-dehydropantoate 2-reductase panE from Bacillus Subtilis==
==Crystal structure of Probable 2-dehydropantoate 2-reductase panE from Bacillus Subtilis==
<StructureSection load='3ego' size='340' side='right' caption='[[3ego]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3ego' size='340' side='right'caption='[[3ego]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ego]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EGO FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EGO FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">panE, apbA, ylbQ, BSU15110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ego FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ego OCA], [https://pdbe.org/3ego PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ego RCSB], [https://www.ebi.ac.uk/pdbsum/3ego PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ego ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3ego TOPSAN]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ego FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ego OCA], [http://pdbe.org/3ego PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ego RCSB], [http://www.ebi.ac.uk/pdbsum/3ego PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ego ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3ego TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PANE_BACSU PANE_BACSU]] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/3ego_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/3ego_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus globigii migula 1900]]
[[Category: Large Structures]]
[[Category: 2-dehydropantoate 2-reductase]]
[[Category: Almo SC]]
[[Category: Almo, S C]]
[[Category: Burley SK]]
[[Category: Burley, S K]]
[[Category: Gheyi T]]
[[Category: Gheyi, T]]
[[Category: Gilmore M]]
[[Category: Gilmore, M]]
[[Category: Hu S]]
[[Category: Hu, S]]
[[Category: Maletic M]]
[[Category: Maletic, M]]
[[Category: Ramagopal UA]]
[[Category: Structural genomic]]
[[Category: Toro R]]
[[Category: Ramagopal, U A]]
[[Category: Toro, R]]
[[Category: Cytoplasm]]
[[Category: Nadp]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Oxidoreductase]]
[[Category: Pane]]
[[Category: Pantothenate biosynthesis]]
[[Category: Probable 2-dehydropantoate 2-reductase]]
[[Category: PSI, Protein structure initiative]]
[[Category: Unknown function]]

Revision as of 11:49, 16 February 2022

Crystal structure of Probable 2-dehydropantoate 2-reductase panE from Bacillus Subtilis

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