3ei7: Difference between revisions

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==Crystal structure of apo-LL-diaminopimelate aminotransferase from Arabidopsis thaliana (no PLP)==
==Crystal structure of apo-LL-diaminopimelate aminotransferase from Arabidopsis thaliana (no PLP)==
<StructureSection load='3ei7' size='340' side='right' caption='[[3ei7]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
<StructureSection load='3ei7' size='340' side='right'caption='[[3ei7]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ei7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EI7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ei7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EI7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ei5|3ei5]], [[3ei6|3ei6]], [[3ei8|3ei8]], [[3ei9|3ei9]], [[3eia|3eia]], [[3eib|3eib]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ei5|3ei5]], [[3ei6|3ei6]], [[3ei8|3ei8]], [[3ei9|3ei9]], [[3eia|3eia]], [[3eib|3eib]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DAP, AGD2, At4g33680, T16L1.170 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DAP, AGD2, At4g33680, T16L1.170 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/LL-diaminopimelate_aminotransferase LL-diaminopimelate aminotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.83 2.6.1.83] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/LL-diaminopimelate_aminotransferase LL-diaminopimelate aminotransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.83 2.6.1.83] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ei7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ei7 OCA], [http://pdbe.org/3ei7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ei7 RCSB], [http://www.ebi.ac.uk/pdbsum/3ei7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ei7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ei7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ei7 OCA], [https://pdbe.org/3ei7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ei7 RCSB], [https://www.ebi.ac.uk/pdbsum/3ei7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ei7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DAPAT_ARATH DAPAT_ARATH]] Required for lysine biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli. Not active with meso-diaminopimelate, lysine or ornithine as substrates.<ref>PMID:16361515</ref> <ref>PMID:21435399</ref>   
[[https://www.uniprot.org/uniprot/DAPAT_ARATH DAPAT_ARATH]] Required for lysine biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli. Not active with meso-diaminopimelate, lysine or ornithine as substrates.<ref>PMID:16361515</ref> <ref>PMID:21435399</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Arath]]
[[Category: Arath]]
[[Category: LL-diaminopimelate aminotransferase]]
[[Category: LL-diaminopimelate aminotransferase]]
[[Category: Large Structures]]
[[Category: Belkum, M J.van]]
[[Category: Belkum, M J.van]]
[[Category: Cherney, M M]]
[[Category: Cherney, M M]]
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