1ufn: Difference between revisions
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<StructureSection load='1ufn' size='340' side='right'caption='[[1ufn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1ufn' size='340' side='right'caption='[[1ufn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ufn]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1ufn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UFN FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 5830484A20 ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 5830484A20 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ufn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufn OCA], [https://pdbe.org/1ufn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ufn RCSB], [https://www.ebi.ac.uk/pdbsum/1ufn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ufn ProSAT], [https://www.topsan.org/Proteins/RSGI/1ufn TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[[ | [[https://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] Defects in Sp110 are a cause of severely impaired resistance to infection by M.tuberculosis.<ref>PMID:15815631</ref> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE]] May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells.<ref>PMID:15815631</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 06:44, 2 March 2022
Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Large Structures
- Lk3 transgenic mice
- Aoki, M
- Arakawa, T
- Carninci, P
- Hayashizaki, Y
- Hirota, H
- Inoue, M
- Kawai, J
- Kigawa, T
- Kobayashi, N
- Koshiba, S
- Matsuda, T
- Matsuo, Y
- Osanai, T
- Structural genomic
- Seki, E
- Shirouzu, M
- Tanaka, A
- Terada, T
- Tochio, N
- Yabuki, T
- Yokoyama, S
- Yoshida, M
- Kdwk motif
- Nuclear protein
- Rsgi
- Sand domain
- Unknown function
