1x45: Difference between revisions
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<StructureSection load='1x45' size='340' side='right'caption='[[1x45]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1x45' size='340' side='right'caption='[[1x45]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1x45]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1x45]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X45 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA1, MINT1, X11 ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA1, MINT1, X11 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x45 OCA], [https://pdbe.org/1x45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x45 RCSB], [https://www.ebi.ac.uk/pdbsum/1x45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x45 ProSAT], [https://www.topsan.org/Proteins/RSGI/1x45 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/APBA1_HUMAN APBA1_HUMAN]] Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:03, 2 March 2022
Solution structure of the first PDZ domain of amyloid beta A4 precursor protein-binding family A, member 1
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human
- Large Structures
- Hayashi, F
- Qin, X R
- Structural genomic
- Yokoyama, S
- Adapter protein xii alpha
- Amyloid beta a4 precursor protein-binding family some
- Endocytosis-exocytosis complex
- Member 1
- National project on protein structural and functional analyse
- Neuron-specific xii protein
- Neuronal munc 18-1-interacting protein 1 mint-1
- Nppsfa
- Pdz domain
- Rsgi
