4hir: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='4hir' size='340' side='right'caption='[[4hir]], [[NMR_Ensembles_of_Models | 32 NMR models]]' scene=''> | <StructureSection load='4hir' size='340' side='right'caption='[[4hir]], [[NMR_Ensembles_of_Models | 32 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4hir]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4hir]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hirme Hirme]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HIR FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6hir|6hir]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6hir|6hir]]</div></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hir OCA], [https://pdbe.org/4hir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hir RCSB], [https://www.ebi.ac.uk/pdbsum/4hir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hir ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/HIRV1_HIRME HIRV1_HIRME]] Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.<ref>PMID:17585879</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 30: | Line 30: | ||
==See Also== | ==See Also== | ||
*[[Hirudin|Hirudin]] | *[[Hirudin 3D structures|Hirudin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||