3hb4: Difference between revisions

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<StructureSection load='3hb4' size='340' side='right'caption='[[3hb4]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
<StructureSection load='3hb4' size='340' side='right'caption='[[3hb4]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hb4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HB4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HB4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hb4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HB4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HB4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E2B:3-{[(9BETA,14BETA,16ALPHA,17ALPHA)-3,17-DIHYDROXYESTRA-1,3,5(10)-TRIEN-16-YL]METHYL}BENZAMIDE'>E2B</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E2B:3-{[(9BETA,14BETA,16ALPHA,17ALPHA)-3,17-DIHYDROXYESTRA-1,3,5(10)-TRIEN-16-YL]METHYL}BENZAMIDE'>E2B</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hb5|3hb5]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hb5|3hb5]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/17-beta-estradiol_17-dehydrogenase 17-beta-estradiol 17-dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.62 1.1.1.62] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hb4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hb4 OCA], [http://pdbe.org/3hb4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hb4 RCSB], [http://www.ebi.ac.uk/pdbsum/3hb4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hb4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hb4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hb4 OCA], [https://pdbe.org/3hb4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hb4 RCSB], [https://www.ebi.ac.uk/pdbsum/3hb4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hb4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DHB1_HUMAN DHB1_HUMAN]] Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.  
[[https://www.uniprot.org/uniprot/DHB1_HUMAN DHB1_HUMAN]] Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Retrieved from "https://proteopedia.org/3hb4"