Sandbox Reserved 1725: Difference between revisions
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=== Vitamin K Cycle === | === Vitamin K Cycle === | ||
[[Image:Vitamin_K_Cycle_IJEV.jpg|300 px|right|thumb|Figure 1. Vitamin K Cycle]] | |||
Vitamin K is essential for blood clotting in the body. The fully reduced form, KH2, allows the gamma carboxylation of blood clotting cofactors and is turned into the epoxide form in the process. Vitamin K epoxide reductase, abbreviated VKOR, turns the epoxide back to the fully reduced form so the reduced form can be used again. This transformation happens in two steps including converting the epoxide to the partially oxidized Vitamin K quinone then converting the quinone to the fully reduced hydroquinone (KH2). <ref name="Stafford">PMID:16102054</ref> | Vitamin K is essential for blood clotting in the body. The fully reduced form, KH2, allows the gamma carboxylation of blood clotting cofactors and is turned into the epoxide form in the process. Vitamin K epoxide reductase, abbreviated VKOR, turns the epoxide back to the fully reduced form so the reduced form can be used again. This transformation happens in two steps including converting the epoxide to the partially oxidized Vitamin K quinone then converting the quinone to the fully reduced hydroquinone (KH2). <ref name="Stafford">PMID:16102054</ref> | ||
=== Structural Overview === | === Structural Overview === | ||
