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==High-resolution structure of the extracellular domain of human CD69==
==High-resolution structure of the extracellular domain of human CD69==
<StructureSection load='3hup' size='340' side='right' caption='[[3hup]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
<StructureSection load='3hup' size='340' side='right'caption='[[3hup]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HUP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HUP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cck|3cck]], [[1fm5|1fm5]], [[1e8i|1e8i]], [[1e87|1e87]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3cck|3cck]], [[1fm5|1fm5]], [[1e8i|1e8i]], [[1e87|1e87]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD69 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD69 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hup OCA], [http://pdbe.org/3hup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hup RCSB], [http://www.ebi.ac.uk/pdbsum/3hup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hup ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hup OCA], [https://pdbe.org/3hup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hup RCSB], [https://www.ebi.ac.uk/pdbsum/3hup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hup ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CD69_HUMAN CD69_HUMAN]] Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.  
[[https://www.uniprot.org/uniprot/CD69_HUMAN CD69_HUMAN]] Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Bezouska, K]]
[[Category: Bezouska, K]]
[[Category: Dohnalek, J]]
[[Category: Dohnalek, J]]

Revision as of 11:57, 30 March 2022

High-resolution structure of the extracellular domain of human CD69

3hup, resolution 1.37Å

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