Sandbox Reserved 1717: Difference between revisions

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[[Image:Vitamin K epoxide.jpg|500 px|right|thumb|Figure 1. Vitamin K Epoxide structure]]
[[Image:Vitamin K epoxide.jpg|500 px|right|thumb|Figure 1. Vitamin K Epoxide structure]]


As mentioned above, Vitamin K epoxide is a part of the Vitamin K cycle and required for blood coagulation. In the cycle, VKOR reduces Vitamin K epoxide to naphthoquinone, or the active form of Vitamin K. In this conversion, VKOR donates electrons to Vitamin K epoxide from the S-H of the active cysteine pair, Cys132-Cys135, discussed above. The active cysteine pair is oxidized in this process. It is returned to its active form with the reduction of the mediated cysteine pairs, Cys43-Cys51.
As discussed in Figure 2, Vitamin K epoxide is a part of the Vitamin K cycle and required for blood coagulation. In the cycle, VKOR reduces Vitamin K epoxide to naphthoquinone, or the active form of Vitamin K. In this conversion, VKOR donates electrons to Vitamin K epoxide from the S-H of the active cysteine pair, Cys132-Cys135, discussed above. The active cysteine pair is oxidized in this process. It is returned to its active form with the reduction of the mediated cysteine pairs, Cys43-Cys51.