7em2: Difference between revisions
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==Crystal structure of the PI5P4Kbeta-XTP complex== | ==Crystal structure of the PI5P4Kbeta-XTP complex== | ||
<StructureSection load='7em2' size='340' side='right'caption='[[7em2]]' scene=''> | <StructureSection load='7em2' size='340' side='right'caption='[[7em2]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EM2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7em2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EM2 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7em2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7em2 OCA], [https://pdbe.org/7em2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7em2 RCSB], [https://www.ebi.ac.uk/pdbsum/7em2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7em2 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CZC:[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl+phosphono+hydrogen+phosphate'>CZC</scene>, <scene name='pdbligand=CZF:[[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>CZF</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7em2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7em2 OCA], [https://pdbe.org/7em2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7em2 RCSB], [https://www.ebi.ac.uk/pdbsum/7em2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7em2 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Senda M]] | [[Category: Senda, M]] | ||
[[Category: Senda T]] | [[Category: Senda, T]] | ||
[[Category: Lipid kinase]] | |||
[[Category: Phosphoinositide signaling]] | |||
[[Category: Transferase]] | |||
