7kyj: Difference between revisions
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==Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc== | ==Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc== | ||
<StructureSection load='7kyj' size='340' side='right'caption='[[7kyj]]' scene=''> | <StructureSection load='7kyj' size='340' side='right'caption='[[7kyj]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KYJ OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[7kyj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KYJ FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA3944 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kyj OCA], [https://pdbe.org/7kyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kyj RCSB], [https://www.ebi.ac.uk/pdbsum/7kyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kyj ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/ATSE3_PSEAE ATSE3_PSEAE]] Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers the peptide Asp-Phe methyl ester (or aspartame) and the peptide antibiotics polymyxin B and colistin. Other substrates like dopamine, serotonin, puromycin, chloramphenicol, D-glucosamine, glycine and N-alpha-acetyl-L-glutamine are used and displayed lower activity.<ref>PMID:23184347</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Becker | [[Category: Becker, D P]] | ||
[[Category: Cymborowski M]] | [[Category: Structural genomic]] | ||
[[Category: Czub | [[Category: Cymborowski, M]] | ||
[[Category: Minor W]] | [[Category: Czub, M P]] | ||
[[Category: Porebski | [[Category: Minor, W]] | ||
[[Category: Reidl | [[Category: Porebski, P J]] | ||
[[Category: Shabalin | [[Category: Reidl, C T]] | ||
[[Category: Shabalin, I G]] | |||
[[Category: Acetyltransferase]] | |||
[[Category: Csgid]] | |||
[[Category: Gnat superfamily]] | |||
[[Category: Pa3944]] | |||
[[Category: Transferase]] | |||
Revision as of 10:19, 13 April 2022
Structure of a GNAT superfamily PA3944 acetyltransferase in complex with zinc
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