Sandbox Reserved 1725: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 5: Line 5:
== Introduction ==
== Introduction ==
Vitamin K epoxide reductase (VKOR) is the enzyme responsible for regenerating vitamin K from vitamin K epoxide to support blood coagulation.  
Vitamin K epoxide reductase (VKOR) is the enzyme responsible for regenerating vitamin K from vitamin K epoxide to support blood coagulation.  
[[Image:Vitamin_K_Cycle_IJEV.jpg|300 px|left|thumb|'''Figure 1. Vitamin K Cycle''' λ-glutamyl carboxylase uses Vitamin KH2 to carboxylate blood clotting cofactors, converting KH2 to KO in the process. Prothrombin is shown as an example of a blood clotting cofactor that later enters the coagulation cascade. VKOR converts KO back to KH2 via two steps with Vitamin K as an intermediate. ]]
[[Image:Vitamin_k_cycle_4.jpg|300 px|left|thumb|'''Figure 1. Vitamin K Cycle''' The three states of Vitamin K are shown along with important enzymes, including VKOR. ]]


=== Vitamin K Cycle ===
=== Vitamin K Cycle ===