Sandbox Reserved 1709: Difference between revisions
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== Disease and Treatment == | == Disease and Treatment == | ||
=== Afflictions === | === Afflictions === | ||
Since activated Vitamin K plays a crucial role in blood coagulation, defects in the function and enzymatic activity of VKOR may detrimentally effect on Vitamin K's ability to promote blood clotting. Mutations in VKOR also increase susceptibility to [https://en.wikipedia.org/wiki/Vascular_disease Vascular Disease], such as a [https://en.wikipedia.org/wiki/Stroke Stroke] <ref>DOI 10.1161/CIRCULATIONAHA.105.580167</ref>. Vitamin K is also important in maintaining bone health with inactivity of VKOR linked to decreased bone density and [https://en.wikipedia.org/wiki/Osteoporosis | Since activated Vitamin K plays a crucial role in blood coagulation, defects in the function and enzymatic activity of VKOR may detrimentally effect on Vitamin K's ability to promote blood clotting. Mutations in VKOR also increase susceptibility to [https://en.wikipedia.org/wiki/Vascular_disease Vascular Disease], such as a [https://en.wikipedia.org/wiki/Stroke Stroke] <ref>DOI 10.1161/CIRCULATIONAHA.105.580167</ref>. Vitamin K is also important in maintaining bone health with inactivity of VKOR linked to decreased bone density and [https://en.wikipedia.org/wiki/Osteoporosis Osteoporosis]<ref>DOI 10.7759/cureus.10816</ref>. | ||
=== Inhibition === | === Inhibition === | ||
[[Image:Warfarin.png |400 px| right| thumb | Figure 4. Structure of Warfarin.]] | [[Image:Warfarin.png |400 px| right| thumb | Figure 4. Structure of Warfarin.]] | ||
