Sandbox Reserved 1716: Difference between revisions

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===Step II===
===Step II===
<scene name='90/904321/Ii/2'>After</scene> Vitamin K Epoxide enters through the isoprenyl-chain tunnel, Asn80 on TM2 and Tyr139 on TM4 <scene name='90/904322/Tyr_asn_binding_warfarin/2'>hydrogen bond</scene>. to Vitamin K Epoxide. When Vitamin K Epoxide binds, there is a shift in the bonds between the cap domain, beta hairpin, and anchor. <scene name='90/904321/Vkobound_cys/1'>Cys135</scene> also forms a disulfide bond with the 3' OH group on Vitamin K Epoxide.  
After Vitamin K Epoxide enters through the isoprenyl-chain tunnel, this begins Step II<scene name='90/904321/Ii/2'>Step II</scene>. Asn80 on TM2 and Tyr139 on TM4 <scene name='90/904322/Tyr_asn_binding_warfarin/2'>hydrogen bond</scene>. to Vitamin K Epoxide. When Vitamin K Epoxide binds, there is a shift in the bonds between the cap domain, beta hairpin, and anchor. <scene name='90/904321/Vkobound_cys/1'>Cys135</scene> also forms a disulfide bond with the 3' OH group on Vitamin K Epoxide.  


===Step III===
===Step III===