3j0a: Difference between revisions

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<SX load='3j0a' size='340' side='right' viewer='molstar' caption='[[3j0a]], [[Resolution|resolution]] 26.00&Aring;' scene=''>
<SX load='3j0a' size='340' side='right' viewer='molstar' caption='[[3j0a]], [[Resolution|resolution]] 26.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3j0a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3J0A FirstGlance]. <br>
<table><tr><td colspan='2'>[[3j0a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J0A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TIL3, TLR5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TIL3, TLR5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3j0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0a OCA], [http://pdbe.org/3j0a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3j0a RCSB], [http://www.ebi.ac.uk/pdbsum/3j0a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0a OCA], [https://pdbe.org/3j0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j0a RCSB], [https://www.ebi.ac.uk/pdbsum/3j0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0a ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN]] Disease susceptibility is associated with variations affecting the gene represented in this entry.  
[[https://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN]] Disease susceptibility is associated with variations affecting the gene represented in this entry.  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN]] Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:11323673</ref>   
[[https://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN]] Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:11323673</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<div class="pdbe-citations 3j0a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3j0a" style="background-color:#fffaf0;"></div>
==See Also==
*[[Toll-like Receptor 3D structures|Toll-like Receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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