Sandbox Reserved 1722: Difference between revisions

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	<scene name='90/904328/Overview_x2_c_pt_3/4'>Cortistatin-14</scene> is one of the peptide ligands that binds to MRGPRX2 (Figure 4B). Cortistatin-14 interacts with the binding pocket through an <scene name='90/904328/Zic14_pt_3/5'>electrostatic</scene> interaction in sub-pocket 1 between Lys-3 on the peptide and Glu-164 and Asp-184 on MRGPRX2 <ref name="Cao"/>. Additionally, there are hydrophobic interactions in sub-pocket 2 between the peptide and the binding pocket due to the large hydrophobic amino acids on Cortistatin-14.		<scene name='90/904328/Overview_x2_c_pt_3/4'>Cortistatin-14</scene> is one of the peptide ligands that binds to MRGPRX2 (Figure 4B). Cortistatin-14 interacts with the binding pocket through an <scene name='90/904328/Zic14_pt_3/5'>electrostatic</scene> interaction in sub-pocket 1 between Lys-3 on the peptide and Glu-164 and Asp-184 on MRGPRX2 <ref name="Cao"/>. Additionally, there are hydrophobic interactions in sub-pocket 2 between the peptide and the binding pocket due to the large hydrophobic amino acids on Cortistatin-14.


	=== 2. MRGPRX2 interaction with G-Protein ===		=== 2. MRGPRX2 interaction with G-Protein ===

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