Methionine synthase: Difference between revisions

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This page is being worked on during the Spring 2022 semester.
This page is being worked on during the Spring 2022 semester.


Addlt ref 1<ref>DOI: 10.1128/JB.00208-06</ref>
'''Methionine synthase''' (MS; EC: 2.1.1.13) is the enzyme in [[one-carbon metabolism]] linking the folate cycle and the methionine cycle. MS catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate (5- me THF) to homocysteine, resulting in the formation of methionine. Methionine is an essential amino acid required by our bodies for healthy cell and tissue growth. It is essential as it is not naturally derived in our bodies. As it is used as a methyl donor in the form of S-adenosylmethionine, the resulting homocysteine is recyled to form methionine again.
 
 
Addlt ref 2<ref>DOI:10.1073/pnas.1133218100</ref>


[[Image:Overall.jpeg]]
[[Image:Overall.jpeg]]
'''Methionine synthase''' (MS; EC: 2.1.1.13) is the enzyme in [[one-carbon metabolism]] linking the folate cycle and the methionine cycle. MS catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate (5- me THF) to homocysteine, resulting in the formation of methionine. Methionine is an essential amino acid required by our bodies for healthy cell and tissue growth. It is essential as it is not naturally derived in our bodies. As it is used as a methyl donor in the form of S-adenosylmethionine, the resulting homocysteine is recyled to form methionine again.


==Function==
==Function==
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<references/>
<references/>
[[Category:One-carbon metabolism]]
[[Category:One-carbon metabolism]]
<ref>DOI: 10.1128/JB.00208-06</ref>
<ref>DOI:10.1073/pnas.1133218100</ref>
Retrieved from "https://proteopedia.org/Methionine_synthase"