BASIL2022GV3HDT: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 43: Line 43:
[[Image:DCMP.png | 400px| left| thumb| dCMP (purple) docked with 3HDT and cofactor ATP (pink) ]]
[[Image:DCMP.png | 400px| left| thumb| dCMP (purple) docked with 3HDT and cofactor ATP (pink) ]]
[[Image:DCMP reaction.png |250px| center|thumb | Binding affinity was increased when hydroxyl group removed from ribose ring on CMP to make dCMP]]
[[Image:DCMP reaction.png |250px| center|thumb | Binding affinity was increased when hydroxyl group removed from ribose ring on CMP to make dCMP]]


Active site containing dCMP and cofactor ATP can be found <scene name='90/904996/Dcmp_with_3hdt_active_site/1'>here</scene> with residues important in substrate binding highlighted in purple (Lys146) and yellow (Leu202).
Active site containing dCMP and cofactor ATP can be found <scene name='90/904996/Dcmp_with_3hdt_active_site/1'>here</scene> with residues important in substrate binding highlighted in purple (Lys146) and yellow (Leu202).