BASIL2022GV3HDT: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 42: | Line 42: | ||
Some of the predicted bind pockets were areas where ATP (red arrow) and dCMP (yellow arrow) binded to with the highest affinity in PyRx. | Some of the predicted bind pockets were areas where ATP (red arrow) and dCMP (yellow arrow) binded to with the highest affinity in PyRx. | ||
[[Image:DCMP.png | 400px| left| thumb| dCMP (purple) docked with 3HDT and cofactor ATP (pink) | [[Image:DCMP.png | 400px| left| thumb| dCMP (purple) docked with 3HDT and cofactor ATP (pink). Visualized in PyMOL<ref>The PyMOL Molecular Graphics System, Version 1.7.4.5 Edu Schrödinger, LLC.</ref>. ]] | ||
[[Image:DCMP reaction.png |250px| center|thumb | Binding affinity was increased when hydroxyl group removed from ribose ring on CMP to make dCMP]] | [[Image:DCMP reaction.png |250px| center|thumb | Binding affinity was increased when hydroxyl group removed from ribose ring on CMP to make dCMP]] | ||
