1btg: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[1btg]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTG OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1BTG FirstGlance].

<table><tr><td colspan='2'>[[1btg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTG OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=1BTG FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=1btg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1btg OCA], [~~http~~://pdbe.org/1btg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1btg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1btg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1btg ProSAT]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=1btg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1btg OCA], [https://pdbe.org/1btg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1btg RCSB], [https://www.ebi.ac.uk/pdbsum/1btg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1btg ProSAT]</td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/NGF_MOUSE NGF_MOUSE]] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.

[[https://www.uniprot.org/uniprot/NGF_MOUSE NGF_MOUSE]] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

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 <StructureSection load='1btg' size='340' side='right'caption='[[1btg]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1btg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1BTG FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1btg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BTG FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1btg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1btg OCA], [http://pdbe.org/1btg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1btg RCSB], [http://www.ebi.ac.uk/pdbsum/1btg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1btg ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1btg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1btg OCA], [https://pdbe.org/1btg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1btg RCSB], [https://www.ebi.ac.uk/pdbsum/1btg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1btg ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/NGF_MOUSE NGF_MOUSE]] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.
+[[https://www.uniprot.org/uniprot/NGF_MOUSE NGF_MOUSE]] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]