Ceramidase: Difference between revisions
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<StructureSection load='2zxc' size='340' side='right' caption="CerN bound to C2 Ceramide [[2zxc]]", [[Resolution|resolution]] 2.20Å' scene='91/910024/2zxc_ballstick/2'> | <StructureSection load='2zxc' size='340' side='right' caption="CerN bound to C2 Ceramide [[2zxc]]", [[Resolution|resolution]] 2.20Å' scene='91/910024/2zxc_ballstick/2'> | ||
== Function == | == Function == | ||
'''CerN''' is an enzyme that catalyzes the cleavage of the [https://en.wikipedia.org/wiki/Sphingolipid Sphingolipid] <scene name='91/910024/Ceramide/3'>Ceramide</scene> at the <scene name='91/910024/Ceramide18/1'>N- | '''CerN''' is an enzyme that catalyzes the cleavage of the [https://en.wikipedia.org/wiki/Sphingolipid Sphingolipid] <scene name='91/910024/Ceramide/3'>Ceramide</scene> at the <scene name='91/910024/Ceramide18/1'>N-acyl linkage</scene>, producing <scene name='91/910024/Ceramide/4'>sphingosine and a fatty acid</scene>.<ref name="Okino">PMID:9603946</ref> <ref>PMID:19088069</ref> | ||
