GLUT1: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 2: | Line 2: | ||
<StructureSection load='4pyp' size='340' side='right' caption='Crystal structure 4PYP from PDB' scene=''> | <StructureSection load='4pyp' size='340' side='right' caption='Crystal structure 4PYP from PDB' scene=''> | ||
==Classification== | == Classification == | ||
GLUT proteins, encoded by the SLC2 genes, are part of the Major Facilitator Superfamily (MFS) of substrate transporters. Structural elements characteristic of GLUT proteins are twelve transmembrane domains, one N-linked glycosylation site, and lengths of about five-hundred amino acids.<ref>PMID:23506862</ref> GLUT proteins transport a variety of monosaccharides that enable cellular respiration and are thus abundant in the body. According to the CATH[http://cathdb.info/version/v4_3_0/superfamily/1.20.1250.20] classification database, the MFS superfamily has 23,982 unique species and 134 domains. | GLUT proteins, encoded by the SLC2 genes, are part of the Major Facilitator Superfamily (MFS) of substrate transporters. Structural elements characteristic of GLUT proteins are twelve transmembrane domains, one N-linked glycosylation site, and lengths of about five-hundred amino acids.<ref>PMID:23506862</ref> GLUT proteins transport a variety of monosaccharides that enable cellular respiration and are thus abundant in the body. According to the CATH[http://cathdb.info/version/v4_3_0/superfamily/1.20.1250.20] classification database, the MFS superfamily has 23,982 unique species and 134 domains. | ||
