Biological Unit: Difference between revisions

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The '''Biological Unit''', also called the '''Biological Assembly'''<ref name="xudunbrackpreprint">[https://www.biorxiv.org/content/10.1101/564385v1.full.pdf Freely available preprint] of Xu and Dunbrack's 2019 "Principles and characteristics of biological assemblies in experimentally determined protein structures".</ref><ref name="xudunbrack">PMID:30965224</ref>, is the ~~quaternary~~ structure that is believed to be the major functional form of a macromolecule. Often it is not the structure contained in the published [[PDB file]], which is called the [[asymmetric unit]]. Therefore it is important to visualize the biological unit in order best to relate function to structure.

The '''Biological Unit''', also called the '''Biological Assembly'''<ref name="xudunbrackpreprint">[https://www.biorxiv.org/content/10.1101/564385v1.full.pdf Freely available preprint] of Xu and Dunbrack's 2019 "Principles and characteristics of biological assemblies in experimentally determined protein structures".</ref><ref name="xudunbrack">PMID:30965224</ref>, is the [[Protein_primary%2C_secondary%2C

_tertiary_and_quaternary_structurequaternary structure]] that is believed to be the major functional form of a macromolecule. Often it is not the structure contained in the published [[PDB file]], which is called the [[asymmetric unit]]. Therefore it is important to visualize the biological unit in order best to relate function to structure.

<!-- I see no biological units at 1h88. Also it is not clear what "natively available" means. Eric Martz April 2010.

Biological units displayed in the 'Structure Boxes' on Proteopedia pages for PDB entries (e.g. [[1h88]]) are those predicted and calculated using the [[PISA|Protein Interfaces, Surfaces and Assemblies Server]] (PISA), as well as all biological unit structures natively available in Proteopedia (i.e. those that were not uploaded by Proteopedia users).

Biological Unit: Difference between revisions

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-The '''Biological Unit''', also called the '''Biological Assembly'''<ref name="xudunbrackpreprint">[https://www.biorxiv.org/content/10.1101/564385v1.full.pdf Freely available preprint] of Xu and Dunbrack's 2019 "Principles and characteristics of biological assemblies in experimentally determined protein structures".</ref><ref name="xudunbrack">PMID:30965224</ref>, is the quaternary structure that is believed to be the major functional form of a macromolecule. Often it is not the structure contained in the published [[PDB file]], which is called the [[asymmetric unit]]. Therefore it is important to visualize the biological unit in order best to relate function to structure.
+The '''Biological Unit''', also called the '''Biological Assembly'''<ref name="xudunbrackpreprint">[https://www.biorxiv.org/content/10.1101/564385v1.full.pdf Freely available preprint] of Xu and Dunbrack's 2019 "Principles and characteristics of biological assemblies in experimentally determined protein structures".</ref><ref name="xudunbrack">PMID:30965224</ref>, is the [[Protein_primary%2C_secondary%2C
+_tertiary_and_quaternary_structurequaternary structure]] that is believed to be the major functional form of a macromolecule. Often it is not the structure contained in the published [[PDB file]], which is called the [[asymmetric unit]]. Therefore it is important to visualize the biological unit in order best to relate function to structure.
 <!-- I see no biological units at 1h88. Also it is not clear what "natively available" means. Eric Martz April 2010.
 Biological units displayed in the 'Structure Boxes' on Proteopedia pages for PDB entries (e.g. [[1h88]]) are those predicted and calculated using the [[PISA|Protein Interfaces, Surfaces and Assemblies Server]] (PISA), as well as all biological unit structures natively available in Proteopedia (i.e. those that were not uploaded by Proteopedia users).